OrganMini 3D volumetric bioprinter
OrganMini 3D volumetric bioprinter

MengziOrganMini 3D volumetric bioprinter

OrganMini is a super-fast and high-activity 3D volumetric bioprinter jointly launched by Newtonoptics and Green Key Biotech. It is the first in China to adopt the inverse CT projection printing principle, which distinguishes it from traditional extrusion-based and layer-by-layer curing printing methods. OrganMini can complete the printing of high-precision, complex three-dimensional models within one minute, with a cell viability rate of over 95%.

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Product Description

Anti-CT projection printing technology

This technology features non-contact and ultra-fast printing capabilities, overcoming the issues of slow printing speed and low cell survival rate associated with traditional contact bioprinters. Additionally, it is easy and quick to operate, with one-step molding, enabling the acquisition of centimeter-scale, highly viable three-dimensional tissues in just one minute.

High viability, High expression

The entire printing process takes place in a sealed printing bottle, utilizing visible light curing for integrated molding, rather than UV curing. It boasts fast printing speeds, no contact damage, no pollution, ensuring that the printed cell models maintain a cell survival rate of over 95% and a high expression levels*.

＊Bernal et al. Advanced materials 2022  

High-precision printing of structures

OrganMini employs a projection printing principle akin to "creating objects out of thin air", eliminating the need for supports or scaffolds to produce intricate three-dimensional models of complex structures such as microvessels, C60, skin, ears, and more. It also facilitates the simultaneous custom printing of multiple three-dimensional models. 

＊MB Xie, et al. Nature Communications, 2023

"One-click printing" software

We have specially designed the Haomiao printing software for OrganMini, which supports multi-user management. The software allows for fine adjustments of parameters such as position, rotation, size, light intensity, duration, and rotation speed. Additionally, the software comes pre-installed with a library of over 200 commonly used models to meet various needs.

 

Organoid construction leading solution

OrganMini boasts three core technological breakthroughs: 60-second ultra-fast integrated printing, which supports the simultaneous printing of multiple organoid microspheres, eliminating the significant batch-to-batch variability inherent in manual operations; Clinical validation has shown that this technology can shorten the organoid construction cycle to 7-14 days, with a drug screening accuracy rate of 83.3%.

Disruptive technology

Case1:The article exploring the mechanism by which ENO2 desensitizes colorectal cancer drugs has been published in Nature Metabolism。 Case2:Exploring the combination of pure silk fibroin ink and volumetric bioprinting, the article has been published in Nature Communication。 Case3:Exploring the relationship between decellularized extracellular matrix (dECM) and volumetric bioprinting, the article has been published in Advanced materials。  

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