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[Newton’s Footsteps] Jupita supports BGI’s single-cell sequencing, ensuring quality control is handled seamlessly in one step.

Release time:

2025-12-08

Source:

Newtonian optics

Newtonian optics

Smart imaging—done in one step!

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BGI Shenzhen

Company Introduction

Shenzhen BGI Co., Ltd. was established on July 9, 2010, with its headquarters located in Yantian District, Shenzhen. The company was listed on the Shenzhen Stock Exchange on July 14, 2017 (stock code: 300676). After more than two decades of development, BGI has become the world’s largest genomics center integrating industry, academia, and research, with operations spanning more than 100 countries and regions worldwide. BGI has always adhered to the corporate vision of “using gene technology to benefit humanity.” Through multi-omics big data technologies—including genetic testing, mass spectrometry, and bioinformatics analysis—we have established a comprehensive, life-cycle health management system covering reproductive health, cancer prevention and control, infectious disease monitoring, and chronic disease management.

BGI

Experimental Background

Gene sequencing technology, which determines the sequence of DNA bases to decode the genetic information they carry, has become a cornerstone tool in modern life sciences. Single-cell sequencing, as an important branch of gene sequencing, enables high-throughput sequencing analysis of genomic, transcriptomic, and epigenomic information at the single-cell level. It can reveal the genetic structure and gene expression status of individual cells, reflecting cellular heterogeneity and playing a crucial role in fields such as oncology, developmental biology, microbiology, and neuroscience.

Highly efficient and precise cell analysis solutions

In single-cell sequencing, the core role of the cell counter lies in its function as a critical initial quality-control step. By providing precise quantification and analysis, it ensures the quality of upstream samples and directly determines the reliability of downstream sequencing data. Using dual-fluorescence staining techniques (such as AO/PI), this method specifically identifies nucleated cells and accurately measures cell concentration, viability, and diameter, effectively eliminating interference from red blood cells, platelets, and cellular debris. Moreover, it can distinguish between intact cells and isolated nuclei—for example, the average diameter of live cells is 13.4 μm, whereas the average diameter of fully separated nuclei is 8.3 μm. Ensure that the samples meet the stringent requirements of single-cell sequencing platforms (e.g., total cell count > 5×10⁵, viability > 70%, clumping rate < 10%). Thus, it ensures from the source the efficiency of single-cell capture as well as the accuracy of subsequent sequencing data.

Newton Optical Cell Analyzer | Fluorescence Analysis Results

As a leading company in China’s gene industry, BGI recently introduced five high-performance cell counters from Newton Optics. These devices will play a crucial role in cutting-edge research fields such as single-cell sequencing.

Newton Optics is honored to contribute to scientific research through BGI. Newton Optics is committed to providing researchers with higher-quality and more convenient experimental solutions.

Product Quick Overview

END

Guangzhou Newton Optics Research Institute Co., Ltd. Located in Tianhe, Guangzhou, this is an innovative enterprise specializing in the application of intelligent imaging technology in the life sciences. The company focuses on the field of cell analysis and has now established a comprehensive R&D, production, and sales system.

Newton Optics adheres to the values of integrity, responsibility, and excellence, and is committed to delivering innovative, cutting-edge scientific tools to customers in the global life sciences field.

Service hotline: 400-9613721

Customer service phone: 15322243697 (WeChat)

Official website: www.newtonoptic.com

R&D Center: Building 1, North Wing, 3rd Floor, No. 38 Gaopu Road, Tianhe District, Guangzhou City

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